Transgenic animals are molecular biology innovative acquired transgenic genes from other species. Transgenic genes means genome contains modified genes or foreign integrated genes from other species with specific characteristics. The first transgenic animal is mouse is the pioneer for this technology.
Methods for production of Transgenic Animals
Frequently using methods for production of transgenic animals are
Microinjection of DNA: In this method transfer of specific gene of interest from specific species in to the pronucleus of reproductive cell by microinjection method. This reproductive cell first cultured in vitro then transferred in to the recipient cell.
Gene Transfer Mediated by Retrovirus: virus is acts as a vector (Retrovirus is also called as RNA virus) for transferring of specific gene of interest.
Gene Transfer by Embryonic Stem Cells: Development and isolation of stem cells, then insertion of gene of interest in to these stem cells and incorporation of these cells in to the host embryo.
Benefits of Transgenic Animals
Benefits in Agriculture: Production of transgenic animals have very good benefits in agriculture fields such as production of transgenic cattle for more milk production, production of disease resistant animals etc.
Benefits in Medical Field: Xeno transplantation is one of the best methods in which non human organs or tissues will transplant in to human recipients. Production of therapeutic products such as insulin, anti blood clotting agents, growth hormones will give better results.
Recombinant DNA technology and transgenic animals will be more beneficial to overcome genetic complications and will give better life in future.