Biomaterials are the things which interact with the biological system mainly with the mammalian tissue. Although many types of biodegradable polymers have been developed but the mechanical properties of these polymers are not well-matched with natural tissues. Biomaterials play an essential role in field of tissue engineering. Tissue engineering is a recently rising biomedical technology and methodology to lend a hand and speed up the regeneration and repairing of defective and damaged tissues.
Biomaterials approaches have been redesigned to imitate the stem cell niche as a way to make stem cells differentiation to the desired cell type. A new type of biomaterial has been developed that very much imitate the mechanical properties of human tissue. The main aim of these new biomaterials is to advance the biocompatibility of blood-contacting devices, to bring out specific cellular functions. These should also help to direct cell-cell interactions both in implants that are initially cell-free, which may provide as matrices to conduct tissue regeneration, and in implants to sustain cell transplantation.  Biomaterial technology plays a significant role in the formation of this cell environment.

These Biomaterials can be used in the biological systems as implants or replacements. These could be artificial hearts, hemodialysis systems, artificial blood vessels etc. Science and engineering can work together to better characterize the cellular microenvironment and then employ this superior knowledge to persuade better tissue scaffolds.

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