Reactive Oxygen Species: Wanted or Unwanted
Aging is a continuous process brought up by many factors such as body’s interaction with the environment, genetic changes in the body, hormonal changes and even chemical changes in proteins, and lipids which bring about changes in appearance of the person. Studies have been carried out extensively all around the world to combat aging and recent studies have shown that modification of signalling or regulatory network suffice to prolong the diseases related to aging.
Molecules containing unpaired highly reactive electrons known as free radicals are thought to be causative agent for aging which is supposed to damage macromolecules. Further studies showed that aerobic metabolism produces superoxide and hydroxyl by-product called reactive oxygen species that cause the modification of proteins, lipids and DNA which has been proved in case of many diseases such as cancer Alzheimer’s and Parkinson’s.
Still there is still a need to carry out huge research efforts to study the exact influence of reactive oxygen species in the aging process as small amounts of reactive oxygen species have shown to increase the life span ought to induce stress response pathway. These finds suggest that this stress response pathway needed to be properly understood in regard of addressing the aging process.